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Anxiety and salivary cortisol levels in patients with burning mouth syndrome: case-control study.

Amenábar JM, Pawlowski J, Hilgert JB, Hugo FN, Bandeira D, Lhüller F, Lopes de Souza MA

Oral Medicine Department, Federal University of Paraná, Brazil. jamenaba@gmail.com

OBJECTIVE: The objective of this study was to evaluate the anxiety and salivary cortisol levels in patients with burning mouth syndrome. STUDY DESIGN: A case-control ed into 2 groups: BMS, with diagnosis of the syndrome, and control, without any complaint of burning mouth. Anamnesis, oral examination, sialometry, the application anxiety inventory, and 3 saliva samples for cortisol analysis were done in every patient. RESULTS: Statistical difference for subjective xerostomia was found on the BMS group (P = .01), but salivary flow rate was normal in both groups. BMS group presented higher anxiety (P = .001) and salivary cortisol levels (P = .003) when compared with the control group. CONCLUSION: Higher anxiety and salivary cortisol levels were positively associated with the presence of BMS.

Published 10 March 2008 in Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 105(4): 460-5.
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